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The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200
PD-L1 expression and regulation by mesenchymal tumor cells remain largely undefined. Here, we report that among different EMT-activated MCF7 human breast cancer cell clones, PD-L1 was differentially upregulated in MCF7 sh-WISP2, MCF7–1001/2101, and MDA-MB-231 cells but not in MCF7 SNAI1 and MCF7 SNA...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Oncoimmunology |
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Prif Awduron: | , , , , , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Taylor & Francis
2017
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5283623/ https://ncbi.nlm.nih.gov/pubmed/28197390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1263412 |
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