Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity

Tumor escape to immunosurveillance and resistance to immune attacks present a major hurdle in cancer therapy, especially in the current era of new cancer immunotherapies. We report here that hypoxia, a hallmark of most solid tumors, orchestrates carcinoma cell heterogeneity through the induction of...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Terry, Stéphane, Buart, Stéphanie, Tan, Tuan Zea, Gros, Gwendoline, Noman, Muhammad Zaeem, Lorens, James B., Mami-Chouaib, Fathia, Thiery, Jean Paul, Chouaib, Salem
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5353930/
https://ncbi.nlm.nih.gov/pubmed/28344883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1271858
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