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Tenofovir alafenamide and elvitegravir loaded nanoparticles for long-acting prevention of HIV-1 vaginal transmission

OBJECTIVE: This report presents tenofovir alafenamide (TAF) and elvitegravir (EVG) fabricated into nanoparticles (NPs) for subcutaneous (SubQ) delivery as prevention strategy. DESIGN: Prospective prevention study in hu-BLT mice. METHODS: Using an oil-in-water emulsion solvent evaporation technique,...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Mandal, Subhra, Prathipati, Pavan K., Kang, Guobin, Zhao, You, Yuan, Zhe, Fan, Wejlin, Li, Qingsheng, Destache, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283613/
https://ncbi.nlm.nih.gov/pubmed/28121666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001349
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