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The neurotoxicity of amyloid β-protein oligomers is reversible in a primary neuron model
Alzheimer’s disease (AD) is characterized by the accumulation of extracellular amyloid β-protein (Aβ) and intracellular hyperphosphorylated tau proteins. Recent evidence suggests that soluble Aβ oligomers elicit neurotoxicity and synaptotoxicity, including tau abnormalities, and play an initiating r...
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| Publicado no: | Mol Brain |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5282621/ https://ncbi.nlm.nih.gov/pubmed/28137266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0284-5 |
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