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Independent movement of the voltage sensors in K(V)2.1/K(V)6.4 heterotetramers

Heterotetramer voltage-gated K(+) (K(V)) channels K(V)2.1/K(V)6.4 display a gating charge-voltage (Q(V)) distribution composed by two separate components. We use state dependent chemical accessibility to cysteines substituted in either K(V)2.1 or K(V)6.4 to assess the voltage sensor movements of eac...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Bocksteins, Elke, Snyders, Dirk J., Holmgren, Miguel
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282584/
https://ncbi.nlm.nih.gov/pubmed/28139741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41646
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