Llwytho...

Polymorphism of apyrimidinic DNA structures in the nucleosome

Huge amounts (>10,000/day) of apurinic/apyrimidinic (AP) sites are produced in genomes, but their structures in chromatin remain undetermined. We determined the crystal structure of the nucleosome containing AP-site analogs at two symmetric sites, which revealed structural polymorphism: one forms...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Osakabe, Akihisa, Arimura, Yasuhiro, Matsumoto, Syota, Horikoshi, Naoki, Sugasawa, Kaoru, Kurumizaka, Hitoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282573/
https://ncbi.nlm.nih.gov/pubmed/28139742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41783
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!