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Dynamic evolution of hepatitis C virus resistance-associated substitutions in the absence of antiviral treatment

Resistance against new hepatitis C virus (HCV) antivirals is an area of increasing interest. Resistance-associated substitutions (RASs) have been identified in treatment-naïve individuals, but pressures driving treatment-independent RAS emergence are poorly understood. We analysed the longitudinal e...

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Publicat a:Sci Rep
Autors principals: Eltahla, Auda A., Leung, Preston, Pirozyan, Mehdi R., Rodrigo, Chaturaka, Grebely, Jason, Applegate, Tanya, Maher, Lisa, Luciani, Fabio, Lloyd, Andrew R., Bull, Rowena A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282498/
https://ncbi.nlm.nih.gov/pubmed/28139734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41719
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