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Genomic characterisation of hepatitis C virus transmitted founder variants with deep sequencing

Transfer of hepatitis C virus (HCV) infection from a donor to a new recipient is associated with a bottleneck of genetic diversity in the transmitted viral variants. Existing data suggests that one, or very few, variants emerge from this bottleneck to establish the infection (transmitted founder [T/...

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Detalhes bibliográficos
Publicado no:Infect Genet Evol
Main Authors: Abayasingam, Arunasingam, Leung, Preston, Eltahla, Auda, Bull, Rowena A., Luciani, Fabio, Grebely, Jason, Dore, Gregory J., Applegate, Tanya, Page, Kimberly, Bruneau, Julie, Cox, Andrea L., Kim, Arthur Y., Schinkel, Janke, Shoukry, Naglaa H., Lauer, Georg M., Maher, Lisa, Hellard, Margaret, Prins, Maria, Lloyd, Andrew, Rodrigo, Chaturaka
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487228/
https://ncbi.nlm.nih.gov/pubmed/30853512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2019.02.032
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