Genomic characterisation of hepatitis C virus transmitted founder variants with deep sequencing

Transfer of hepatitis C virus (HCV) infection from a donor to a new recipient is associated with a bottleneck of genetic diversity in the transmitted viral variants. Existing data suggests that one, or very few, variants emerge from this bottleneck to establish the infection (transmitted founder [T/...

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Publicado en:Infect Genet Evol
Main Authors: Abayasingam, Arunasingam, Leung, Preston, Eltahla, Auda, Bull, Rowena A., Luciani, Fabio, Grebely, Jason, Dore, Gregory J., Applegate, Tanya, Page, Kimberly, Bruneau, Julie, Cox, Andrea L., Kim, Arthur Y., Schinkel, Janke, Shoukry, Naglaa H., Lauer, Georg M., Maher, Lisa, Hellard, Margaret, Prins, Maria, Lloyd, Andrew, Rodrigo, Chaturaka
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487228/
https://ncbi.nlm.nih.gov/pubmed/30853512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2019.02.032
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