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Genomic characterisation of hepatitis C virus transmitted founder variants with deep sequencing

Transfer of hepatitis C virus (HCV) infection from a donor to a new recipient is associated with a bottleneck of genetic diversity in the transmitted viral variants. Existing data suggests that one, or very few, variants emerge from this bottleneck to establish the infection (transmitted founder [T/...

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Dettagli Bibliografici
Pubblicato in:Infect Genet Evol
Autori principali: Abayasingam, Arunasingam, Leung, Preston, Eltahla, Auda, Bull, Rowena A., Luciani, Fabio, Grebely, Jason, Dore, Gregory J., Applegate, Tanya, Page, Kimberly, Bruneau, Julie, Cox, Andrea L., Kim, Arthur Y., Schinkel, Janke, Shoukry, Naglaa H., Lauer, Georg M., Maher, Lisa, Hellard, Margaret, Prins, Maria, Lloyd, Andrew, Rodrigo, Chaturaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487228/
https://ncbi.nlm.nih.gov/pubmed/30853512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2019.02.032
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