Dynamic evolution of hepatitis C virus resistance-associated substitutions in the absence of antiviral treatment

Resistance against new hepatitis C virus (HCV) antivirals is an area of increasing interest. Resistance-associated substitutions (RASs) have been identified in treatment-naïve individuals, but pressures driving treatment-independent RAS emergence are poorly understood. We analysed the longitudinal e...

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Publicado en:Sci Rep
Autores principales: Eltahla, Auda A., Leung, Preston, Pirozyan, Mehdi R., Rodrigo, Chaturaka, Grebely, Jason, Applegate, Tanya, Maher, Lisa, Luciani, Fabio, Lloyd, Andrew R., Bull, Rowena A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282498/
https://ncbi.nlm.nih.gov/pubmed/28139734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41719
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