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Mitigated NSAID-induced apoptotic and autophagic cell death with Smad7 overexpression

Non-steroidal anti-inflammatory drugs damaged gastrointestinal mucosa in cyclooxygenase-dependent and -independent pathway, among which apopototic or autophagic cell death in gastrointestinal cells might be one of key cytotoxic mechanisms responsible for NSAID-induced damages. Therefore, alleviating...

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Detalhes bibliográficos
Publicado no:J Clin Biochem Nutr
Main Authors: Lee, Ho-Jae, Park, Jong Min, Hahm, Ki Baik
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5281534/
https://ncbi.nlm.nih.gov/pubmed/28163383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.16-69
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