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Sensitization of multidrug-resistant cancer cells to Hsp90 inhibitors by NSAIDs-induced apoptotic and autophagic cell death

NSAIDs (non-steroidal anti-inflammatory drugs) have potential use as anticancer agents, either alone or in combination with other cancer therapies. We found that NSAIDs including celecoxib (CCB) and ibuprofen (IBU) significantly potentiated the cytotoxicity of Hsp90 inhibitors in human multidrug-res...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Moon, Hyun-Jung, Kim, Hak-Bong, Lee, Su-Hoon, Jeun, So-Eun, Kang, Chi-Dug, Kim, Sun-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5834263/
https://ncbi.nlm.nih.gov/pubmed/29541415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24130
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