IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells

The pathogenic process of intervertebral disc degeneration (IDD) is characterized by imbalance in the extracellular matrix (ECM) metabolism. Nucleus pulposus (NP) cells have important roles in maintaining the proper structure and tissue homeostasis of disc ECM. These cells need adequate supply of gl...

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Bibliografiset tiedot
Julkaisussa:Cell Death Discov
Päätekijät: Wu, Xinghuo, Song, Yu, Liu, Wei, Wang, Kun, Gao, Yong, Li, Shuai, Duan, Zhenfeng, Shao, Zengwu, Yang, Shuhua, Yang, Cao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5280875/
https://ncbi.nlm.nih.gov/pubmed/28149534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.107
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