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HMGB1-induced autophagy promotes extracellular matrix degradation leading to intervertebral disc degeneration

Intervertebral disc degeneration (IDD) remains a leading cause of adult disability. High mobility group box l (HMGB1) is a nuclear DNA-binding protein and acts as a central mediator of inflammation. The purpose of this study was to investigate the effect of HMGB1 in IDD. In our study, IDD interverte...

詳細記述

保存先:
書誌詳細
出版年:Int J Clin Exp Pathol
主要な著者: Fu, Biao, Lu, Xia, Zhao, Er-Yang, Wang, Ji-Xin, Peng, Si-Min
フォーマット: Artigo
言語:Inglês
出版事項: e-Century Publishing Corporation 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539879/
https://ncbi.nlm.nih.gov/pubmed/33042328
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