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HMGB1-induced autophagy promotes extracellular matrix degradation leading to intervertebral disc degeneration
Intervertebral disc degeneration (IDD) remains a leading cause of adult disability. High mobility group box l (HMGB1) is a nuclear DNA-binding protein and acts as a central mediator of inflammation. The purpose of this study was to investigate the effect of HMGB1 in IDD. In our study, IDD interverte...
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| Udgivet i: | Int J Clin Exp Pathol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
e-Century Publishing Corporation
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7539879/ https://ncbi.nlm.nih.gov/pubmed/33042328 |
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