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IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells

The pathogenic process of intervertebral disc degeneration (IDD) is characterized by imbalance in the extracellular matrix (ECM) metabolism. Nucleus pulposus (NP) cells have important roles in maintaining the proper structure and tissue homeostasis of disc ECM. These cells need adequate supply of gl...

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Bibliografiske detaljer
Udgivet i:Cell Death Discov
Main Authors: Wu, Xinghuo, Song, Yu, Liu, Wei, Wang, Kun, Gao, Yong, Li, Shuai, Duan, Zhenfeng, Shao, Zengwu, Yang, Shuhua, Yang, Cao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5280875/
https://ncbi.nlm.nih.gov/pubmed/28149534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.107
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