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The Spleen Is an Ideal Site for Inducing Transplanted Islet Graft Expansion in Mice

Alternative islet transplantation sites have the potential to reduce the marginal number of islets required to ameliorate hyperglycemia in recipients with diabetes. Previously, we reported that T cell leukemia homeobox 1 (Tlx1)(+) stem cells in the spleen effectively regenerated into insulin-produci...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Itoh, Takeshi, Nishinakamura, Hitomi, Kumano, Kenjiro, Takahashi, Hiroyuki, Kodama, Shohta
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279780/
https://ncbi.nlm.nih.gov/pubmed/28135283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170899
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