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The Spleen Is an Ideal Site for Inducing Transplanted Islet Graft Expansion in Mice

Alternative islet transplantation sites have the potential to reduce the marginal number of islets required to ameliorate hyperglycemia in recipients with diabetes. Previously, we reported that T cell leukemia homeobox 1 (Tlx1)(+) stem cells in the spleen effectively regenerated into insulin-produci...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Itoh, Takeshi, Nishinakamura, Hitomi, Kumano, Kenjiro, Takahashi, Hiroyuki, Kodama, Shohta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279780/
https://ncbi.nlm.nih.gov/pubmed/28135283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170899
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