Pretreatment of donor islets with papain improves allograft survival without systemic immunosuppression in mice

Although current immunosuppression protocols improve the efficacy of clinical allogenic islet transplantation, T cell-mediated allorejection remains unresolved, and major histocompatibility complexes (MHCs) play a crucial role in this process. Papain, a cysteine protease, has the unique ability to c...

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Detalhes bibliográficos
Publicado no:Islets
Main Authors: Kumano, Kenjiro, Nishinakamura, Hitomi, Mera, Toshiyuki, Itoh, Takeshi, Takahashi, Hiroyuki, Fujiwara, Toshiyoshi, Kodama, Shohta
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5029203/
https://ncbi.nlm.nih.gov/pubmed/27618231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2016.1223579
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