Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts

Current three-dimensional (3D) genome modeling platforms are limited by their inability to account for radial placement of loci in the nucleus. We present Chrom3D, a user-friendly whole-genome 3D computational modeling framework that simulates positions of topologically-associated domains (TADs) rel...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Paulsen, Jonas, Sekelja, Monika, Oldenburg, Anja R., Barateau, Alice, Briand, Nolwenn, Delbarre, Erwan, Shah, Akshay, Sørensen, Anita L., Vigouroux, Corinne, Buendia, Brigitte, Collas, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278575/
https://ncbi.nlm.nih.gov/pubmed/28137286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1146-2
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