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Laminopathy-causing lamin A mutations reconfigure lamina-associated domains and local spatial chromatin conformation
The nuclear lamina contributes to the regulation of gene expression and to chromatin organization. Mutations in A-type nuclear lamins cause laminopathies, some of which are associated with a loss of heterochromatin at the nuclear periphery. Until recently however, little if any information has been...
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| Pubblicato in: | Nucleus |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5973257/ https://ncbi.nlm.nih.gov/pubmed/29517398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2018.1449498 |
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