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Lipodystrophic laminopathy: Lamin A mutation relaxes chromatin architecture to impair adipogenesis
The familial partial Dunnigan lipodystrophy, characterized by subcutaneous fat loss, is frequently caused by an R482W mutation in lamin A. In this issue, Oldenburg et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201701043) demonstrate that this mutation impairs the ability of lamin A to repr...
में बचाया:
| में प्रकाशित: | J Cell Biol |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Rockefeller University Press
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584192/ https://ncbi.nlm.nih.gov/pubmed/28811278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707090 |
| टैग : |
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