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Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency
A likely mechanism of chromosomal rearrangement formation involves joining the ends from two different chromosomal double-strand breaks (DSBs). These events could potentially be mediated by either of two end-joining (EJ) repair pathways [canonical nonhomologous end joining (C-NHEJ) or alternative en...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5278456/ https://ncbi.nlm.nih.gov/pubmed/28057860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612204114 |
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