Quantitation of prenylcysteines by a selective cleavage reaction.

The allylic thioether bond of the prenylcysteines of prenylated proteins has been shown to be cleaved by 2-naphthol under alkaline conditions to yield substituted naphthopyrans. These products are readily resolved from interfering materials by HPLC and have a strongly absorbing chromophore. Thus, th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Epstein, W W, Lever, D, Leining, L M, Bruenger, E, Rilling, H C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52779/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946384/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9668
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