Celecoxib and 2,5‐dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β‐catenin signaling pathway

We previously reported that celecoxib, a selective COX‐2 inhibitor, strongly inhibited human colon cancer cell proliferation by suppressing the Wnt/β‐catenin signaling pathway. 2,5‐Dimethylcelecoxib (DM‐celecoxib), a celecoxib analog that does not inhibit COX‐2, has also been reported to have an ant...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Egashira, Issei, Takahashi‐Yanaga, Fumi, Nishida, Risa, Arioka, Masaki, Igawa, Kazunobu, Tomooka, Katsuhiko, Nakatsu, Yoshimichi, Tsuzuki, Teruhisa, Nakabeppu, Yusaku, Kitazono, Takanari, Sasaguri, Toshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5276826/
https://ncbi.nlm.nih.gov/pubmed/27761963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13106
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