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Mismatch Repair Deficient Mice Show Susceptibility to Oxidative Stress-Induced Intestinal Carcinogenesis

We have previously established an experimental system for oxidative DNA damage-induced tumorigenesis in the small intestine of mice. To elucidate the roles of mismatch repair genes in the tumor suppression, we performed oxidative DNA damage-induced tumorigenesis experiments using Msh2-deficient mice...

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Bibliographic Details
Main Authors: Piao, Jingshu, Nakatsu, Yoshimichi, Ohno, Mizuki, Taguchi, Ken-ichi, Tsuzuki, Teruhisa
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879593/
https://ncbi.nlm.nih.gov/pubmed/24391453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.5750
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