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Inhibition of GSK‐3β increases trabecular bone volume but not cortical bone volume in adenine‐induced uremic mice with severe hyperparathyroidism

Patients with chronic kidney disease (CKD) are at increased risk for bone fractures compared with the general population. Repression of the Wnt/β‐catenin signaling pathway is associated with bone abnormalities. Inhibition of glycogen synthase kinase (GSK)‐3β, a critical component of the Wnt/β‐cateni...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Tatsumoto, Narihito, Arioka, Masaki, Yamada, Shunsuke, Takahashi‐Yanaga, Fumi, Tokumoto, Masanori, Tsuruya, Kazuhiko, Kitazono, Takanari, Sasaguri, Toshiyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112491/
https://ncbi.nlm.nih.gov/pubmed/27803315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13010
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