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Alpha-Ketoglutarate as a Molecule with Pleiotropic Activity: Well-Known and Novel Possibilities of Therapeutic Use

Alpha-ketoglutarate (AKG), an endogenous intermediary metabolite in the Krebs cycle, is a molecule involved in multiple metabolic and cellular pathways. It functions as an energy donor, a precursor in the amino acid biosynthesis, a signalling molecule, as well as a regulator of epigenetic processes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Arch Immunol Ther Exp (Warsz)
Hauptverfasser: Zdzisińska, Barbara, Żurek, Aleksandra, Kandefer-Szerszeń, Martyna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274648/
https://ncbi.nlm.nih.gov/pubmed/27326424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00005-016-0406-x
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