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Hyperreactivity of Blood Leukocytes in Patients with NAFLD to Ex Vivo Lipopolysaccharide Treatment Is Modulated by Metformin and Phosphatidylcholine but Not by Alpha Ketoglutarate

INTRODUCTION AND AIMS: Toll-like receptor 4 and proinflammatory cytokines play a central role in the progression of nonalcoholic fatty liver disease. We investigated IL-1, IL-6 and TNFα production and toll-like receptor 4 in both—obese and lean patients with non-alcoholic fatty liver disease who met...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zwolak, Agnieszka, Szuster-Ciesielska, Agnieszka, Daniluk, Jadwiga, Słabczyńska, Olga, Kandefer-Szerszeń, Martyna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4667886/
https://ncbi.nlm.nih.gov/pubmed/26629827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143851
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