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Limitations in plasticity of the T-cell receptor repertoire.

How constrained is T-cell recognition? Is a truncated T-cell receptor (TCR) repertoire, missing half of its V beta components (where V indicates variable), still broad enough to produce an antigen-specific T-cell response to all determinants? These questions can be answered for certain T-cell antige...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Nanda, N K, Apple, R, Sercarz, E
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719532/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.21.9503
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