Dominant T-cell-receptor beta chain variable region V beta 14+ clones in juvenile rheumatoid arthritis.

The characteristic histopathology and major histocompatibility complex associations in juvenile rheumatoid arthritis suggest an oligoclonal antigen-specific T-cell population may be critical to pathogenesis. To test this, we analyzed the T-cell repertoire of a polyarticular HLA-DR4+ juvenile rheumat...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Grom, A A, Thompson, S D, Luyrink, L, Passo, M, Choi, E, Glass, D N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248215/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.23.11104
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