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Design of a randomized controlled trial for genomic carrier screening in healthy patients seeking preconception genetic testing

Population-based carrier screening is limited to well-studied or high-impact genetic conditions for which the benefits may outweigh the associated harms and costs. As the cost of genome sequencing declines and availability increases, the balance of risks and benefits may change for a much larger num...

詳細記述

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書誌詳細
出版年:Contemp Clin Trials
主要な著者: Kauffman, Tia L., Wilfond, Benjamin S., Jarvik, Gail P., Leo, Michael C., Lynch, Frances L., Reiss, Jacob A., Richards, C. Sue, McMullen, Carmit, Nickerson, Deborah, Dorschner, Michael O., Goddard, Katrina A.B.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274557/
https://ncbi.nlm.nih.gov/pubmed/27940182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.12.007
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