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Design of a randomized controlled trial for genomic carrier screening in healthy patients seeking preconception genetic testing

Population-based carrier screening is limited to well-studied or high-impact genetic conditions for which the benefits may outweigh the associated harms and costs. As the cost of genome sequencing declines and availability increases, the balance of risks and benefits may change for a much larger num...

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Detalhes bibliográficos
Publicado no:Contemp Clin Trials
Main Authors: Kauffman, Tia L., Wilfond, Benjamin S., Jarvik, Gail P., Leo, Michael C., Lynch, Frances L., Reiss, Jacob A., Richards, C. Sue, McMullen, Carmit, Nickerson, Deborah, Dorschner, Michael O., Goddard, Katrina A.B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274557/
https://ncbi.nlm.nih.gov/pubmed/27940182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.12.007
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