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Design of a randomized controlled trial for genomic carrier screening in healthy patients seeking preconception genetic testing

Population-based carrier screening is limited to well-studied or high-impact genetic conditions for which the benefits may outweigh the associated harms and costs. As the cost of genome sequencing declines and availability increases, the balance of risks and benefits may change for a much larger num...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Contemp Clin Trials
Κύριοι συγγραφείς: Kauffman, Tia L., Wilfond, Benjamin S., Jarvik, Gail P., Leo, Michael C., Lynch, Frances L., Reiss, Jacob A., Richards, C. Sue, McMullen, Carmit, Nickerson, Deborah, Dorschner, Michael O., Goddard, Katrina A.B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274557/
https://ncbi.nlm.nih.gov/pubmed/27940182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2016.12.007
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