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The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation

A dynamic, properly organised actin cytoskeleton is critical for the production and haemostatic function of platelets. The Wiskott Aldrich Syndrome protein (WASp) and Actin-Related Proteins 2 & 3 Complex (Arp2/3 complex) are critical mediators of actin polymerisation and organisation in many cel...

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Détails bibliographiques
Publié dans:Platelets
Auteurs principaux: Thomas, Steven G., Poulter, Natalie S., Bem, Danai, Finney, Brenda, Machesky, Laura M., Watson, Stephen P.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5274539/
https://ncbi.nlm.nih.gov/pubmed/27778524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09537104.2016.1235688
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