Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response

Patients with leukemia who receive a T cell–depleted allogeneic stem cell graft followed by postponed donor lymphocyte infusion (DLI) can experience graft-versus-leukemia (GVL) reactivity, with a lower risk of graft-versus-host disease (GVHD). Here, we have investigated the magnitude, diversity, and...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: van Bergen, Cornelis A.M., van Luxemburg-Heijs, Simone A.P., de Wreede, Liesbeth C., Eefting, Matthijs, von dem Borne, Peter A., van Balen, Peter, Heemskerk, Mirjam H.M., Mulder, Arend, Claas, Fransiscus H.J., Navarrete, Marcelo A., Honders, Wilhelmina M., Rutten, Caroline E., Veelken, Hendrik, Jedema, Inge, Halkes, Constantijn J.M., Griffioen, Marieke, Falkenburg, J.H. Frederik
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272193/
https://ncbi.nlm.nih.gov/pubmed/28067665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86175
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