Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response

Patients with leukemia who receive a T cell–depleted allogeneic stem cell graft followed by postponed donor lymphocyte infusion (DLI) can experience graft-versus-leukemia (GVL) reactivity, with a lower risk of graft-versus-host disease (GVHD). Here, we have investigated the magnitude, diversity, and...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: van Bergen, Cornelis A.M., van Luxemburg-Heijs, Simone A.P., de Wreede, Liesbeth C., Eefting, Matthijs, von dem Borne, Peter A., van Balen, Peter, Heemskerk, Mirjam H.M., Mulder, Arend, Claas, Fransiscus H.J., Navarrete, Marcelo A., Honders, Wilhelmina M., Rutten, Caroline E., Veelken, Hendrik, Jedema, Inge, Halkes, Constantijn J.M., Griffioen, Marieke, Falkenburg, J.H. Frederik
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5272193/
https://ncbi.nlm.nih.gov/pubmed/28067665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86175
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