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Intentional donor lymphocyte-induced limited acute graft-versus-host disease is essential for long-term survival of relapsed acute myeloid leukemia after allogeneic stem cell transplantation

The prognosis of patients with relapsed acute myeloid leukemia after allogeneic transplantation is poor. We hypothesized that initial disease control by effective cytoreduction, followed by rapid induction of a profound allo-immune response by donor-lymphocyte infusion during the neutropenic phase,...

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Detalhes bibliográficos
Main Authors: Eefting, Matthias, von dem Borne, Peter A, de Wreede, Liesbeth C, Halkes, Constantijn JM, Kersting, Sabina, Marijt, Erik WA, Veelken, Hendrik, Falkenburg, JH Frederik
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971086/
https://ncbi.nlm.nih.gov/pubmed/24241493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.089565
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