Intentional donor lymphocyte-induced limited acute graft-versus-host disease is essential for long-term survival of relapsed acute myeloid leukemia after allogeneic stem cell transplantation

The prognosis of patients with relapsed acute myeloid leukemia after allogeneic transplantation is poor. We hypothesized that initial disease control by effective cytoreduction, followed by rapid induction of a profound allo-immune response by donor-lymphocyte infusion during the neutropenic phase,...

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Hlavní autoři: Eefting, Matthias, von dem Borne, Peter A, de Wreede, Liesbeth C, Halkes, Constantijn JM, Kersting, Sabina, Marijt, Erik WA, Veelken, Hendrik, Falkenburg, JH Frederik
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2014
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971086/
https://ncbi.nlm.nih.gov/pubmed/24241493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.089565
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