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Models of human metastatic colon cancer in nude mice orthotopically constructed by using histologically intact patient specimens.

There is an important need for clinically relevant animal models for human cancers. Toward this goal, histologically intact human colon-cancer specimens derived surgically from patients were implanted orthotopically to the colon or cecum of nude mice. We have observed extensive orthotopic growth in...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Fu, X Y, Besterman, J M, Monosov, A, Hoffman, R M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1924398/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.20.9345
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