Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells

Expansion of mesenchymal stromal/stem cells (MSCs) used in clinical practices may be associated with accumulation of genetic instability. Understanding temporal and mechanistic aspects of this process is important for improving stem cell therapy protocols. We used γH2AX foci as a marker of a genetic...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Pustovalova, Margarita, Grekhova, Anna, Astrelina, Tatiana, Nikitina, Viktoria, Dobrovolskaya, Ekaterina, Suchkova, Yulia, Kobzeva, Irina, Usupzhanova, Darya, Vorobyeva, Natalia, Samoylov, Aleksandr, Bushmanov, Andrey, Ozerov, Ivan V., Zhavoronkov, Alex, Leonov, Sergey, Klokov, Dmitry, Osipov, Andreyan N.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270682/
https://ncbi.nlm.nih.gov/pubmed/27959319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101142
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