Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging

We assessed the effects of donor age on clonogenicity, proliferative potential, and spontaneous γH2AX foci in the proliferating (Ki67 +) and senescent (SA β-gal +) cultures of skin fibroblasts isolated from 34 donors of different age (23-82 years). Here, we demonstrated that neither the colony formi...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zorin, Vadim, Grekhova, Anna, Pustovalova, Margarita, Zorina, Alla, Smetanina, Nadezhda, Vorobyeva, Natalia, Kopnin, Pavel, Gilmutdinova, Ilmira, Moskalev, Alexey, Osipov, Andreyan N., Leonov, Sergey
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660037/
https://ncbi.nlm.nih.gov/pubmed/31289256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102067
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