Spontaneous γH2AX foci in human dermal fibroblasts in relation to proliferation activity and aging

We assessed the effects of donor age on clonogenicity, proliferative potential, and spontaneous γH2AX foci in the proliferating (Ki67 +) and senescent (SA β-gal +) cultures of skin fibroblasts isolated from 34 donors of different age (23-82 years). Here, we demonstrated that neither the colony formi...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Zorin, Vadim, Grekhova, Anna, Pustovalova, Margarita, Zorina, Alla, Smetanina, Nadezhda, Vorobyeva, Natalia, Kopnin, Pavel, Gilmutdinova, Ilmira, Moskalev, Alexey, Osipov, Andreyan N., Leonov, Sergey
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660037/
https://ncbi.nlm.nih.gov/pubmed/31289256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102067
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