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The Ciliopathy Gene ahi1 Is Required for Zebrafish Cone Photoreceptor Outer Segment Morphogenesis and Survival

PURPOSE: Joubert syndrome (JBTS) is an autosomal recessive ciliopathy with considerable phenotypic variability. In addition to central nervous system abnormalities, a subset of JBTS patients exhibit retinal dystrophy and/or kidney disease. Mutations in the AHI1 gene are causative for approximately 1...

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Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Lessieur, Emma M., Fogerty, Joseph, Gaivin, Robert J., Song, Ping, Perkins, Brian D.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270624/
https://ncbi.nlm.nih.gov/pubmed/28118669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20326
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