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The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry
BACKGROUND: RRx-001, a dinitroazetidine derivative, is a novel anticancer agent currently in phase II clinical trials. It mediates immunomodulatory effects either directly through polarization of tumor associated macrophages or indirectly through vascular normalization and increased T-lymphocyte inf...
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| Publicado no: | Clin Epigenetics |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270305/ https://ncbi.nlm.nih.gov/pubmed/28149332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0312-z |
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