Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master regulatory transcription factor that plays an important role in the antioxidant response pathway against anticancer drug-induced cytotoxic effects. RRx-001 is a new anticancer agent that generates reactive oxygen and nitrogen species, an...

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Vydáno v:Oncotarget
Hlavní autoři: Ning, Shoucheng, Sekar, Thillai Veerapazham, Scicinski, Jan, Oronsky, Bryan, Peehl, Donna M., Knox, Susan J., Paulmurugan, Ramasamy
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673285/
https://ncbi.nlm.nih.gov/pubmed/26280276
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