RRx-001, A novel dinitroazetidine radiosensitizer

The ‘holy grail’ in radiation oncology is to improve the outcome of radiation therapy (RT) with a radiosensitizer—a systemic chemical/biochemical agent that additively or synergistically sensitizes tumor cells to radiation in the absence of significant toxicity. Similar to the oxygen effect, in whic...

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Vydáno v:Invest New Drugs
Hlavní autoři: Oronsky, Bryan, Scicinski, Jan, Ning, Shoucheng, Peehl, Donna, Oronsky, Arnold, Cabrales, Pedro, Bednarski, Mark, Knox, Susan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2016
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859863/
https://ncbi.nlm.nih.gov/pubmed/26841903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-016-0326-y
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