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Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase

[Image: see text] Inhibitor design incorporating features of the reaction coordinate and transition-state structure has emerged as a powerful approach for the development of enzyme inhibitors. Such inhibitors find use as mechanistic probes, chemical biology tools, and therapeutics. Endo-α-1,2-mannos...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Am Chem Soc
Main Authors: Petricevic, Marija, Sobala, Lukasz F., Fernandes, Pearl Z., Raich, Lluís, Thompson, Andrew J., Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhu, Sha, Sollogoub, Matthieu, Jiménez-Barbero, Jesús, Rovira, Carme, Davies, Gideon J., Williams, Spencer J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2016
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269645/
https://ncbi.nlm.nih.gov/pubmed/27992199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10075
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