Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase

[Image: see text] Inhibitor design incorporating features of the reaction coordinate and transition-state structure has emerged as a powerful approach for the development of enzyme inhibitors. Such inhibitors find use as mechanistic probes, chemical biology tools, and therapeutics. Endo-α-1,2-mannos...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Petricevic, Marija, Sobala, Lukasz F., Fernandes, Pearl Z., Raich, Lluís, Thompson, Andrew J., Bernardo-Seisdedos, Ganeko, Millet, Oscar, Zhu, Sha, Sollogoub, Matthieu, Jiménez-Barbero, Jesús, Rovira, Carme, Davies, Gideon J., Williams, Spencer J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5269645/
https://ncbi.nlm.nih.gov/pubmed/27992199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b10075
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados