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Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes

Streptokinase is a virulence factor of streptococci and acts as a plasminogen activator to generate the serine protease plasmin which promotes bacterial metastasis. Streptokinase isolated from group C streptococci has been used therapeutically as a thrombolytic agent for many years and its mechanism...

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Pubblicato in:PLoS One
Autori principali: Huish, Sian, Thelwell, Craig, Longstaff, Colin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5268773/
https://ncbi.nlm.nih.gov/pubmed/28125743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170936
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